The Heel-Prick Test Your Newborn Already Had in Frankfurt, and Why You Never Heard the Results

The Neugeborenenscreening, a small blood sample taken from your newborn's heel, is a genuinely separate official process in Hessen from the U-Untersuchungen check-ups, and in Hessen it's actually processed right in Frankfurt, at the Screening-Zentrum Hessen, part of the Universitätsklinikum Frankfurt's Hessisches Kindervorsorgezentrum, working on behalf of the Hessian Ministry for Family, Seniors, Sports, Health and Care. The center screens every sample submitted for congenital metabolic and hormonal disorders, severe congenital immune defects (SCID), cystic fibrosis, sickle cell disease, and spinal muscular atrophy, and Hessen also offers an additional extended metabolic screening on top of the nationwide standard program, under the state's own child health protection law. All lab analyses are completed the same day a sample is received, for samples that arrive by 10 a.m. Monday through Saturday, so the turnaround itself is genuinely fast. What confuses a lot of newcomer parents: a normal, unremarkable result generally isn't proactively sent to you, you have to actually reach out to hear it, and the center's own contact details, phone, fax, and email, are there specifically for parents or doctors who want to follow up rather than wait and wonder.

The Official Rule

The Neugeborenenscreening gets confused with the U-Untersuchungen constantly, especially by newcomer parents navigating Germany’s check-up schedule for the first time, but in Hessen it’s actually a genuinely separate official process, and it’s processed right here in Frankfurt.

A small blood sample is taken from your newborn’s heel, and in Hessen it’s sent to a dedicated screening center based in the city. The Screening-Zentrum Hessen, part of Universitätsklinikum Frankfurt’s Hessisches Kindervorsorgezentrum, processes every sample submitted across the state, working on behalf of the Hessian Ministry for Family, Seniors, Sports, Health and Care, rather than through your Kinderarzt’s own practice.

What Hessen's newborn screening actually covers
AspectDetail
Where samples are processedScreening-Zentrum Hessen, Universitätsklinikum Frankfurt
Standard conditions screenedCongenital metabolic and hormonal disorders, SCID, cystic fibrosis, sickle cell disease, spinal muscular atrophy
Hessen's own extended programAdditional metabolic disorders, set by the Hessian Child Care Advisory Board
Turnaround timeSame day, for samples received by 10 a.m., Monday through Saturday
Normal result communicationNot sent automatically, you need to ask

The screening panel is genuinely broad, and Hessen adds its own extended layer on top of the nationwide standard. The standard program covers congenital metabolic and hormonal disorders, severe congenital immune defects (SCID), cystic fibrosis, sickle cell disease, and spinal muscular atrophy. On top of that, Hessen’s own extended metabolic screening program is available under the state’s own child health protection law, with the additional conditions checked determined by the Hessian Child Care Advisory Board, rather than left to individual hospitals to decide.

The turnaround is genuinely fast, which matters given how time-sensitive these conditions can be. All lab analyses at the Screening-Zentrum Hessen are completed on the same day a sample is received, provided it arrives by 10 a.m., Monday through Saturday. That speed is part of why early detection through this specific system can genuinely change outcomes for the conditions it’s built to catch.

The detail that catches a lot of newcomer parents off guard: a normal result generally isn’t proactively communicated to you at all. Unlike a doctor’s appointment where you’d expect a follow-up call either way, the screening center’s own structure means an unremarkable finding is only shared if you or your Kinderarzt specifically ask, rather than being pushed out to you automatically. If you haven’t heard anything and want confirmation, reaching out directly to the Screening-Zentrum Hessen is the way to actually get an answer.

A newborn's feet resting on a blanket in a hospital crib, with an identification band visible on the ankle

Photo by Vidal Balielo Jr. on Pexels

What Real People Say

Parents new to Frankfurt describe genuine confusion in the first days after birth, unsure whether the heel-prick sample and the early U-Untersuchungen were the same thing, several mention realizing only afterward that the screening runs through a completely separate center rather than their Kinderarzt’s own office.

Parents who never heard back about their baby’s screening result describe some real anxiety before they learned that silence is actually the expected outcome for a normal result, several specifically recommend just calling the Screening-Zentrum Hessen directly if you want confirmation rather than assuming no news is bad news.

Step by Step

  1. Understand the heel-prick test is genuinely separate from the U2, U3, and other early check-ups, even though it happens around the same time.
  2. Know that in Hessen, your baby’s sample goes to the Screening-Zentrum Hessen at Universitätsklinikum Frankfurt, not your Kinderarzt’s own practice.
  3. Don’t expect a call for a normal result, this is the expected default, not a sign anything was missed.
  4. If you want direct confirmation, contact the Screening-Zentrum Hessen yourself, or ask your Kinderarzt to follow up on your behalf.
  5. Ask your Kinderarzt about Hessen’s extended metabolic screening program if you want to understand exactly what’s covered beyond the nationwide standard panel.

Compliance Note

This page explains the general framework for newborn screening in Hessen, current as of mid-2026. It is not medical advice, and specific results and follow-up steps should always be confirmed with your Kinderarzt or the Screening-Zentrum Hessen directly.

FAQ & Common Pitfalls

Is the heel-prick test the same thing as the U2 or U3 check-up?

No, it's a genuinely separate process. The Neugeborenenscreening is a specific blood test processed through a dedicated screening center rather than as part of a regular U-Untersuchung appointment with your Kinderarzt, even though both happen in your newborn's first days of life.

Who actually processes the sample in Hessen, and where?

The Screening-Zentrum Hessen, part of the Hessisches Kindervorsorgezentrum at Universitätsklinikum Frankfurt, processes every sample submitted in Hessen, working on behalf of the Hessian Ministry for Family, Seniors, Sports, Health and Care.

Does Hessen test for anything beyond the standard nationwide conditions?

Yes. Alongside the standard program set by the Gemeinsamer Bundesausschuss, the nationwide joint committee of doctors and health insurers, Hessen offers an additional extended metabolic screening under its own state child health protection law, with the specific conditions checked determined by the Hessian Child Care Advisory Board.

Why haven't we heard anything about our baby's results?

That's actually expected if the result was unremarkable. The screening center's own guidance is that a normal result generally isn't proactively communicated, you or your Kinderarzt need to actively reach out to the Screening-Zentrum Hessen to confirm it, rather than waiting for a call that isn't coming.